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Validation study of Exiqon's miRCURY LNA™ Universal RT microRNA PCR product line concludes that Exiqon's PCR products are 10 times as sensitive as the comparable products provided by main competitor

02-11-10 kl. 2/11 2010 07:00 | Exiqon 17,80 (0,00%)

Exiqon A/S (NASDAQ OMX: EXQ), a leading supplier of high-value gene expression
analysis products, today announced that Toumy Guettouche, Ph.D., Director,
Oncogenomics Core Facility, Sylvester Cancer Center, University of Miami School
of Medicine, USA, has presented data from a larger validation study of Exiqon's
miRCURY LNA™ Universal RT microRNA PCR product line.

Data in support of Exiqon's platform were presented at the qPCR Symposium, San
Francisco, California, USA, on 1 November 2010.

Exiqon's microRNA PCR product line is being used for microRNA expression
profiling in a variety of sample types including difficult samples like blood
serum and FFPE.

“Dr. Guettouche has demonstrated that Exiqon's microRNA PCR platform allows for
quantitative detection of a higher number of microRNAs at low concentrations
compared to similar products offered by a main competitor”, said Dr. Peter
Mouritzen, Director R&D at Exiqon, and added: “The superiority of our microRNA
PCR assays is obtained by applying our proprietary LNA™ technology according to
a very advanced bioinformatics algorithm which took us years to develop”.

The study demonstrated that of the 311 microRNA qPCR assays common to the two
technologies, 73% of Exiqon's qPCR primer sets amplified cDNA from the
equivalent of 5 copies of microRNA whereas 50 copies were needed for a 70% call
from the competitive product.

“Exiqon's microRNA PCR products were launched a year ago, and we have since had
a very successful market uptake”, said Henrik M. Pfundheller, Vice President
Sales & Marketing at Exiqon, and added: “The key performance criteria that
makes the customers buy our products are the robust quantitative and sensitive
capabilities without the need for pre-amplification combined with the ease of
use”.

Toumy Guettouche, who is heading the core facility at University of Miami
School of Medicine, will now add Exiqon's microRNA PCR panels to their product
offering. “We now offer the Universal RT microRNA qPCR panels at our facility”,
said Dr. Toumy Guettouche.

The miRCURY LNA™ Universal RT microRNA PCR product line includes more than
1,000 pre-validated assays offered as Ready-to-Use qPCR panels for human, mouse
and rat, single microRNA assays, reagents, software and protocols for all major
qPCR instruments. The advanced assay design tool and the LNA™ technology is
also available through Exiqon's homepage to researchers who want to design
their own microRNA assays for example for microRNAs discovered through next
generation sequencing.

Additional information:
Lars Kongsbak, President and CEO, tel. +45 4566 0888 (cell: +45 4090 2101)
Henrik M. Pfundheller, VP Sales & Marketing, tel. +45 4565 0420 (cell: +45 4090
2106)

See the full release in the attached PDF or at www.exiqon.com/investor/portal




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