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26/10 16:03 af AaBforever |
Ja spændende om den ryger over 2900 i dag:-)
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26/10 14:14 af ProInvestorNEWS |
Gasforvirring på det internationale marked, Kinas aktiemarked i nedsmeltning og danske regnskabsvitaminer til investorerne. Lyt med i afsnit 141, hvor Hansen og Larsen bl.a. kommer ind på flere store danske virksomheder som Danske Bank, Ørsted og A.P. Møller - Mærsk. (link)
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26/10 11:22 af ProInvestorNEWS |
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26/10 10:50 af Svingtraderen |
Med partneren Janssens godkendelse tirsdag af kræftmidlet Tecvayli i USA, har Genmab fået en ekstra kilde til indtjening, der vil medvirke til, at selskabet bliver endnu mindre afhængig af sin supersællert Darzalex.
Det konstaterer analytiker i Sydbank Søren Løntoft Hansen, efter at den amerikanske lægemiddelstyrelse tirsdag godkendte Tecvayli til uhelbredeligt syge patienter med knoglemarvskræft, der i forvejen har modtaget mindst fire andre behandlinger.
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26/10 09:53 af E L |
'Bernadette King, a J&J spokesperson, told Endpoints via email that in its clinical trial, the average patient was treated for 9 to 10 months. Based on this, the total cost of therapy ranges between a list price of $355,000 and $395,000 – or $39,500 per month.'........ (link)
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26/10 07:13 af bibob |
Artiklen fra FDA. (link)
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26/10 06:57 af GeorgeBest |
Kate Sasser (som ofte er blevet fremhævet af JvdW), forlader Genmab og har fået job hos Tempus. Tempus er en af Genmabs partnere. Kilde LinkedIn.
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26/10 06:51 af ProInvestorNEWS |
Genmab: Janssen får godkendt middel
baseret på duobody (link)
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26/10 06:33 af Darvin |
U.S. Food and Drug Administration (FDA) approved TECVAYLI™ (teclistamab-cqyv) for the treatment of adult patients with relapsed or refractory multiple myeloma
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26/10 06:32 af Darvin |
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26/10 06:19 af Stroka |
God morgen. :-)
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26/10 06:12 af ProInvestorNEWS |
USA/lukning: Rentefald sendte aktier op - Tesla, Apple i front
(link)
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26/10 06:11 af ProInvestorNEWS |
Godmorgen :-)
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26/10 05:58 af Helge Larsen/PI-redaktør |
Godmorgen :-)
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25/10 21:47 af Sukkeralf |
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25/10 13:58 af bikube |
Tak.
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25/10 13:49 af bikube |
Hvad er royalti% til Genmab på Kesimpta?
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25/10 12:18 af E L |
Genmab-middel tæt på blockbustersstatus – Novartis øger salget 172 pct (link)
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25/10 10:57 af ProInvestorNEWS |
Få overblik over de mange kommende regnskaber med ProInvestors Finanskalender. (link)
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25/10 10:14 af E L |
yes, because of the old one is why i doubted, but it seems legit (link)
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25/10 10:13 af Sukkeralf |
Nice and exciting - something new to dig into
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25/10 10:10 af Bulder |
anti-glycan seems new. The other is from 2001
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25/10 10:09 af E L |
scancell +33% so must be a new deal
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25/10 10:05 af E L |
is this something real or did someone mix up old news....?
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25/10 09:58 af E L |
Genmab and Scancell Announce Cancer Antibody Product Collaboration — First Disease Target Identified (link)
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25/10 09:58 af E L |
must be something new, an 'antitbody' ;-)
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25/10 09:57 af E L |
Scancell signs exclusive deal with cancer giant Genmab for anti-glycan antitbody (link)
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25/10 09:52 af E L |
in % y/y strongest grower for Novartis, in $$ the second strongest. will be a blockbuster this year already
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25/10 09:46 af Sukkeralf |
Flot momentum - begynder at sigte mod 1,2-1,5 milliarder næste år
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25/10 08:36 af ProInvestorNEWS |
Selskaber shortet på det danske aktiemarked pr. 24/10-2022 (link)
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24/10 16:00 af E L |
kkjoel, our south-east asia correspondent ;-)
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24/10 14:37 af kkjoel |
Ja.. samt et par ekstra småinf. om de Japanske operationer, som ikke vælter en bagover...
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24/10 14:36 af Bulder |
Tak kkjoel. Der var altså ikke noget nyt hvad angår feltet udenfor cancer. Det han siger her, har han sagt før.
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24/10 14:32 af kkjoel |
While setting up an independent system in Japan, Genmab appears to be more cautious about its move in China. “This is, of course, a market that we don’t want to ignore,” he said, but he added that in China, the company will be working with partners based on licensing strategies. [SLUT]
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24/10 14:32 af kkjoel |
The Japan arm now has a workforce of over 50 and growing. It plans to add more people as it gears up to establish a scheme for solo development and commercialization...
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24/10 14:31 af kkjoel |
Both are being investigated in global PIII trials, with no timeline disclosed for Japan filing...
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24/10 14:31 af kkjoel |
In Japan, some Genmab-originated medicines are already available through partners, but not via its Japan outpost. Farthest along in development towards its first stand-alone product approval are two drug candidates. One is tisotumab vedotin, an antibody-drug conjugate (ADC) for cervical cancer, which is approved in the US under the brand name of Tivdak. The other is the bispecific antibody epcoritamab for the treatment of non-Hodgkin’s lymphoma...
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24/10 14:31 af kkjoel |
[Nyt afsnit] 50-Plus Employees in Japan...
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24/10 14:30 af kkjoel |
to prune costs...
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24/10 14:30 af kkjoel |
In the meantime, Dr van de Winkel also spoke about ways to address the challenge of rising drug prices seen in tandem with the diversification of modalities, stressing the need to curb R&D and manufacturing costs to ensure access to medicines. “I think we need to develop medicines more effectively and in shorter periods of time in the future,” said the CEO, explaining that Genmab is looking into an approach to work with data science companies to shorten the development process thereby...
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24/10 14:30 af kkjoel |
“The Japanese system is complex and it’s dynamic, but I would argue that also the US system is very complex and dynamic. I mean, there was recent legislation, which is potentially completely changing the reimbursement of medicines in the US,” he said. “Europe is even more difficult to navigate,” he continued, explaining that it takes years for some countries to set prices for new medicines. “I would say that Japan is not necessarily more complex than other systems,” he added...
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24/10 14:29 af kkjoel |
Japan has an advanced healthcare system that reimburses for innovative medicines, he said, while also expressing hopes for collaborations with academic and other research institutes...
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24/10 14:29 af kkjoel |
On Japan, Dr van de Winkel said that it is a “priority market” alongside the US, with these two being the only countries where Genmab is building out its independent commercial infrastructure. Cancer medicines often fall victim to big price slashes under market expansion re-pricing rules in Japan, but he said that the market is “still very attractive” for innovative companies...
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24/10 14:29 af kkjoel |
[Nyt afsnit] Japan Still Attractive...
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24/10 14:28 af kkjoel |
Introducing these two examples, Dr van de Winkel highlighted the potential of the company’s drug discovery technologies for the development of products in other therapeutic areas. With increasing profitability, Genmab is now prepping an R&D foray into one additional disease space. “We have not yet finally decided where to go,” said the CEO, noting that the company is testing out multiple candidates preclinically to see which ones could be brought into the clinic for further development...
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24/10 14:28 af kkjoel |
Already now, two of the six Genmab technology-based products are on the market outside of cancer. Kesimpta and Tepezza were initially developed by the biotech as cancer therapies, but their licensing partners repurposed them for multiple sclerosis and thyroid eye disease, respectively, during the development process...
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24/10 14:28 af kkjoel |
“We have a growing, what we call, recurring income stream (from royalties), which is getting bigger and bigger and bigger. So, we actually are quite well off from a capital perspective. We can actually then use that capital to invest in creating new products and holding onto more product rights,” said Dr van de Winkel in a Tokyo interview on October 21...
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24/10 14:27 af kkjoel |
Its current pipeline boasts 20 assets. In recent years, the company has been pivoting away from its original pure out-licensing scheme towards a business model based on codevelopment and stand-alone commercialization, which started to financially pay off from last year. Cancer medicines will remain the growth driver of the company in the coming years...
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24/10 14:27 af kkjoel |
Since its inception 23 years ago, the Copenhagen-headquartered biotech has originated 40 pipeline candidates, of which six have been approved to date via partner firms. Among them are major products such as Novartis’ Kesimpta (ofatumumab) and Arzerra (ofatumumab), Janssen’s Darzalex (daratumumab) and Horizon Therapeutics’ Tepezza (teprotumumab)...
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24/10 14:27 af kkjoel |
Genmab, a Danish antibody developer focused on oncology, is set to expand its R&D into a new therapeutic area, with the specific target field to be announced next year. The company will harness its bispecific and hexamer formation platforms and steady revenue stream to now generate drugs for non-cancer diseases, CEO Jan van de Winkel told Jiho...
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