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20/3 10:43 af Bulder |
The epco data in the table from ash is a snapshot from July 6.
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20/3 10:34 af E L |
i am not sure if this Glofitamab data is new after ASH; it says data cutoff August 3 2020, have to look into it
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20/3 10:15 af Bulder |
So all in all, efficacy not worse, safety better, and sc convenience. My opinion.
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20/3 10:13 af Bulder |
ORR was 100% at the 48 mg dose (epco)
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20/3 10:10 af Bulder |
But fewer pts in the epco abstract from ash
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20/3 10:09 af Bulder |
ORR seems to be similar (link)
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20/3 10:06 af Bulder |
E L do you remeber efficacy on epco?
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20/3 10:05 af Bulder |
Jeg kan ikke lige huske, hvad epco præsterer på effekt-siden, men havde ingen CRS over grade 2 (link)
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20/3 09:56 af E L |
it was march OPEX yesterday, Quadruple witching, in a FED week, whole market saw large volumes.
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20/3 08:47 af Helge Larsen/PI-redaktør |
God morgen. :-)
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20/3 08:29 af JørgenVarnæs |
Imponerende data
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20/3 00:12 af GeorgeBest |
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20/3 00:11 af GeorgeBest |
Glofitamab, a Novel, Bivalent CD20-Targeting T-Cell–Engaging Bispecific Antibody, Induces Durable Complete Remissions in Relapsed or Refractory B-Cell Lymphoma: A Phase I Trial
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19/3 23:09 af Bulder |
Volumen var især voldsom i de sidste minutter, hvor der tilsyneladende blev solgt ud.
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19/3 22:36 af ungeee |
@Pensionisten. Fredag GEN 2200 holdt ikke. Jeg satser dog på de 2200 først i næste uge. TRYG er nu overstået, hvilket jeg også tænker ZEAL mærkede i dag. Hvis GEN er mere rentefølsom end jeg egentlig tror OG hvis renten stiger meget næste uge, bliver de 2200 måske alligevel svært - men Carpe Diem :)
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19/3 22:09 af w |
Voldsom omsætning i US noteringen.
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19/3 21:42 af AaBforever |
Men måske et tegn......who knows....what to come?
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19/3 21:36 af AaBforever |
Pensionisten..ved det godt....har været med i mange år. Var bare et sjovt lille kuriosum efter så meget negativt den sidste tid.
Kursen landede jo hvor den gjorde????
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19/3 21:07 af E L |
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19/3 19:18 af bikube |
Selv om jeg læste korrektur, inden jeg sendte, er der alligevel en fejl. Det er Multipel Sclerose, det er godkendt til.
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19/3 18:52 af bikube |
JnJ har fået FDA godkendelse af Ponesimod mod RS. Er det mon en direkte konkurrent til OFA.
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19/3 18:49 af AaBforever |
I starten af luk-auktionen fra buddet 3635???
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19/3 18:19 af Helge Larsen/PI-redaktør |
Fredagens aktier: Bavarian og Netcompany til tops på coronahåb (link)
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19/3 15:46 af Vitus |
Ingen interesserer sig for Genmab idag....al interesse ligger hos Bavarian...
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19/3 11:24 af Sukkeralf |
We just need BergenBio to show the way for AXL - and then some small obscure biotech can licence Enapotamab for some smaller indications
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19/3 11:23 af Sukkeralf |
The same goes for the IL8 compound - but it still has a long way to go. But still alive and kicking
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19/3 11:19 af E L |
@Sukkeralf who knows what they'll make from Enapotamab years from now ;) Teprotumumab was also thought to be dead... you have to be a bit lucky as well when someone else develops your oldies ;)
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19/3 11:17 af JørgenVarnæs |
In turn, for investors that means catching the programs around the time we see efficacy in phase 1/2
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19/3 11:15 af E L |
i agree
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19/3 11:11 af JørgenVarnæs |
But times have changed - I don’t believe we will see phase 3 programs fail as epicly as we did 10 years ago with ie zalutumumab. Today it is more a question of bringing the programs to market before the competition
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19/3 11:09 af JørgenVarnæs |
The great thing about a diversified portfolio is the ability to soak up the shock effect from these failures.
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19/3 11:08 af Optimistus |
@Stockbull 01:44, så havde M.Lykketoft måske alligevel ret dengang (-:
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19/3 11:07 af E L |
(is that even a real term, realistically optimistic, or did i just make that up lol)
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19/3 11:06 af E L |
I think it is fair to expect a few failures in the years to come, like Enapotamab failed. The art will be to detect them early before they cost too much... disappointments happen, but Genmab's hit-ratio is high so far, making me realistically optimistic
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19/3 11:05 af Sukkeralf |
Agree - but at least zalu lives on in Amivantamab
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19/3 11:00 af JørgenVarnæs |
But I’m guessing the real lesson was Zalu falling flat on it’s stomach - hope we will not see similar things with the programs we retain ownership over in the years to come
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19/3 10:54 af E L |
well then let me say it in a different way, the buyer probably made a lot of money...
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19/3 10:43 af JørgenVarnæs |
...there is a hole in that business model, but I can’t seem to put my finger on it....
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19/3 10:41 af JørgenVarnæs |
Purchase price usd 240m - sales price usd 10m....
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19/3 10:38 af JørgenVarnæs |
In the end, I think the whole thing was written off - and the sales amount was very close to zero. The real cost was the diversion from the core business of Genmab - development of new drugs
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19/3 10:36 af Plimsoller |
True, but along the way between then and now, it could have resulted in bankruptcy. It is forgotten :-D
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19/3 10:27 af E L |
seriously; had they been able to hold on to that factory, they would have probably made a lot of money on it now.... but let's forget that quickly again ;-)
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19/3 10:26 af E L |
@Plimsoller blocked ! ;-)
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19/3 10:17 af Plimsoller |
E L. Should Genmab help them and buy a .... :-)
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19/3 10:13 af Helge Larsen/PI-redaktør |
Spørgsmål til Q&A er meget velkommen. :-)
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19/3 10:02 af E L |
yep. really will depend on production...
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19/3 10:01 af JørgenVarnæs |
Wow - look at that range on the 2021 revenue expectations!!
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19/3 09:59 af E L |
also hoping to get Tepezza production back up in the next few weeks.... (link)
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19/3 09:59 af JørgenVarnæs |
Would be nice with some real news. GEN has not been pampering us lately...
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19/3 09:57 af E L |
and we must be really close to the EC approval of Kesimpta and Dara amyloidosis
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