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11/12 11:38 af GeorgeBest |
@Bulder. Jan will probably say it is a Janssen product, and refer the analyst to them.
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11/12 11:37 af ProInvestorNEWS |
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11/12 11:28 af Bulder |
(link) talquetamab
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11/12 11:17 af Bulder |
Seems like a little concern over the fatal infections in the tec-dara-len combo. One covid and one sepsis. Hope this will be discussed on R&D Day.
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11/12 10:35 af E L |
PET scan for Richters / epco (link)
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11/12 09:59 af E L |
Ash 2022 – talquetamab heads to the regulators (link)
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11/12 09:55 af E L |
It's a while ago this was written 'Assuming epco gets approved, and 1 biontech duobody, then for these first 9 Genmab approved antibodies, 8 of them will be blockbusters, Kesimpta will be multiple blockbuster, Teclistamab, Talquetamab, Tepezza now are prognosed for >$4bn and Dara and Rybrevant >$5bn. That is just unheard of for a biotech.' but seems fully on track... maybe Mim8 will be #9 though, as GB suggested or even Inclacumab...
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11/12 09:33 af E L |
Janssen Presents New Data for Talquetamab, a First-in-Class GPRC5DxCD3 Bispecific Antibody, Suggesting Durable Responses in Patients with Heavily Pretreated Multiple Myeloma (link)
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11/12 09:30 af E L |
Janssen Presents First Data from MajesTEC-2 Trial of TECVAYLI (teclistamab-cqyv) in Combination with DARZALEX FASPRO (daratumumab and hyaluronidase-fihj) and Lenalidomide in Relapsed or Refractory Multiple Myeloma (link)
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11/12 08:37 af ProInvestorNEWS |
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11/12 08:31 af Stroka |
Det ser godt ud for talquetamab og teclistamab.
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11/12 08:28 af Stroka |
God morgen :-)
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11/12 08:11 af ProInvestorNEWS |
MyelomaTeacher - Cindy Chmielewski
@MyelomaTeacher
Hope - for RRMM
(link)
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11/12 08:05 af ProInvestorNEWS |
Ben Derman
@bdermanmd
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11 t
Rub some ‘DRT’ on it. MajesTEC-2 with Dara/Len/Tec. ORR 93.5% in a less refractory population with high rates of CR (55%). No data on mrd negativity among the CR population. But definitely makes a case for combination strategies for teclistamab(link)
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11/12 08:00 af ProInvestorNEWS |
oseph Mikhael
@jmikhaelmd
master presenter Ajai Chari presenting Talquetamab a bispecific antibody targeting GPRC5D. Amazing 74% ORR and even more remarkable low infection rates grade 3/4 at 17% and 12%. This is remarkable and may likely be the next bispecific and First GPRC5D available (link)
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11/12 07:58 af ProInvestorNEWS |
Raj Chakraborty
@rajshekharucms
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11 t
Although I am super excited about teclistamab combinations in earlier lines of therapy, 6.25% fatal AEs 2/2 infection in Dara-Tec-Len is concerning. Need to develop new strategies to mitigate infection risk such that greater efficacy is not neutralized by high tox (link)
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11/12 07:54 af ProInvestorNEWS |
'New lease on life' for blood cancer patients as experimental therapy treats 73 PERCENT of patients in global clinical trials
The treatment targets recurring multiple myeloma, a type of blood cancer
More than 30 percent of trial patients saw all traces of their cancer disappear
Talquetamab work as well or better than similar multiple myeloma treatments (link)
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11/12 06:52 af Helge Larsen/PI-redaktør |
Godmorgen. :-)
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11/12 01:17 af GeorgeBest |
Exciting responses to bispecific epcoritamab for Richter's transformed CLL, which can be very tricky to treat (link)
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10/12 13:30 af gentogen |
Nu vi er ved det, så er efterbehandlngen af Lu AF82422 in Participants With Multiple System Atrophy (AMULET) netop blevet forlænget. Ikke at man kan lægge ret meget i det, men måske alligevel et lille positivt tegn???
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10/12 10:30 af E L |
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10/12 09:37 af Helge Larsen/PI-redaktør |
Positive Early Results of Mim8 Pave Way for Testing in Phase 3 Trials (link)
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10/12 09:30 af Helge Larsen/PI-redaktør |
Enig GB. Det er vildt og imponerende.
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10/12 08:41 af GeorgeBest |
Ret vildt at tænke på at når Epco og Talquetamab bliver godkendte i løbet af næste år, vil der være 8 Genmab udviklede produkter på markedet. Hvad mon bliver nr. 9. Mim8 fra Novo??
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10/12 08:29 af GeorgeBest |
Volume på Genmab ADS var vist ekstraordinær høj i går - næsten 1.4 mill. omsat
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10/12 07:41 af ProInvestorNEWS |
Godmorgen :-) Opdateret status oversigt for det Danske OMX C25 Index fra NordStock fredag d. 9. december - købs- og salgsignaler: (link)
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10/12 01:05 af gentogen |
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10/12 01:04 af gentogen |
The anti-interleukin (IL)-8 monoclonal antibody, BMS-986253 combined with nivolumab showed preliminary activity in melanoma progressing on checkpoint inhibitors, as reported in a phase I/II trial presented at ESMO Immuno-Oncology Congress 2022
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9/12 17:49 af gdn55 |
Derfor er jeg langsigtet, har haft Genmab siden kurs 35,60.
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9/12 17:48 af gdn55 |
Men stiger fra 1875 til godt 3300 fra først i junni
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9/12 17:39 af Vitus |
Sådan tænker jeg ikke, når Genmab falder fra over kurs 3000 til under kurs 2000…
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9/12 17:16 af Vitus |
Ja, så er det godt man har APM og Vestas ….
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9/12 16:20 af nohope |
Man skulle tro det var Novo der havde indsendt en BLA.
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9/12 16:07 af Sukkeralf |
Thats really nice
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9/12 15:41 af E L |
just a year after teclistamab; that was dec21 (and approved oct22)
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9/12 15:38 af E L |
Janssen Submits Biologics License Application to U.S. FDA for Talquetamab for the Treatment of Patients with Relapsed or Refractory Multiple Myeloma (link)
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9/12 15:04 af JKY_VH |
:-D Bulder
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9/12 15:03 af GeorgeBest |
5 years looks okay for. Can I get the same return the next 5 years, I’ll be happy :-)
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9/12 14:55 af nohope |
You are probably right, we have to go back 10 years to make it look great.I can´t do 10 years, but this 5 years compared to Novo, which steadily pays annual dividend.(link)
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9/12 14:47 af StockBull |
Im ok with the moon
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9/12 14:37 af Bulder |
The sky above nohope is always black.
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9/12 14:35 af GeorgeBest |
Well, the sky has been quite blue the last 10 years. Why would you make it grey then?
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9/12 14:18 af nohope |
The problem with Mygind is that according to him then is the sky over Genmab is not just always blue, it is luminiscent.
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9/12 13:44 af Bulder |
Nsclc er en svær øvelse (link)
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9/12 12:37 af E L |
"Genmab: Præsenterede torsdag data for Gen1042 der var bedre end forventet" (link) -I still can't find anything about it; we'll probably have to wait for the R&D day
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9/12 12:36 af E L |
Genmab rider på en bølge af succes
David Mygind
Fredag 09. december (link)
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9/12 07:49 af GeorgeBest |
#ASH22 Talquetamab, a GPRC5D x CD3 Bispecific Antibody, in Patients with RRMM. At 0.4 mg/kg/week: ORR 73%, median PFS 7.5 months. (link)
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9/12 07:24 af Stroka |
God morgen :-)
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9/12 07:18 af Helge Larsen/PI-redaktør |
Godmorgen :-)
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9/12 03:29 af Doublo |
God morgen fra Tyrkiet klart du må starte før kl. 5 Helge,
eller kunne du slet ikke nå det du når.
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