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25/4 15:46 af E L |
@Sukkeralf Feb25: let's move on to Judith to speak a bit about timing for 1042 - - Yes, thank you. And thank you for the question. So as we put in the slide, it's by 2025. I cannot be more precise at this point because, as you know, durability is key for IL. And we need to assess durability on first line and then, undergo the prioritization within our own pipeline. And head and neck externally is moving as well. And we will come with all these data sets more likely by the second half of the year
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25/4 15:05 af E L |
so can we estimate roughly $100mn total for the quarter for Epkinly? vs Roche Columvi 60m+ Lunsumio 21m=81CHF
=~$89mn
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25/4 14:15 af Solsen |
Husk Abbvie rapporterer Epkinly med noget revenue og en del som profit share.
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25/4 14:13 af Solsen |
I Q424 var samme rapporterede tal $40 mln. Så 25-30% q/q stigning på epkinly.
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25/4 14:07 af Solsen |
Global Elahere net revenues were $179 million
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25/4 14:07 af Solsen |
Abbvie rapporterer $51 mln i Q125 for epkinley. Fremgang på 90% ift ssamme kvartal sidste år.
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25/4 09:04 af Sukkeralf |
Hvornår mon Genmab/BioNTech har tænkt sig at give os data på GEN1042. Håber på enten ASCO eller EHA - og drømmen er stadig at de overrasker. Eller skal vi mon helt frem til efteråret ved SITC eller ESMO. Nogen der ved noget?
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24/4 17:30 af Raun |
Thank you E L for t
his emotional story
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24/4 16:59 af E L |
this patient still surviving on epcoritamab (link)
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24/4 15:41 af E L |
'Halozyme sues Merck over alleged patent infringement' -
everyone sueing everyone in this industry :(
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24/4 13:26 af E L |
The data showed anti-tumor activity, delayed tumor outgrowth and prolonged survival for the combination treatment compared to both single treatments. The immunomodulatory activity of BNT314/GEN1059 was further potentiated in combination with PD-1 blockade.
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24/4 13:26 af E L |
BioNTech at AACR 2025 -Preclinical data for the EpCAMx4-1BB antibody candidate BNT314/GEN1059, which is being developed in collaboration with Genmab S/A (“Genmab”), will be presented in a poster session. BNT314/GEN1059 was evaluated in combination with PD-1 inhibition in a tumor model unresponsive to each single treatment. (link)
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24/4 12:51 af Solsen |
Ikke meget udvikling i Ocrevus salget ud over prisstigning. De to andre bispecific heller ikke imponerende. Håber Kesimpta og Epco kan udvise lidt bedre tendenser.
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24/4 11:57 af E L |
Roche Ocrevus sales Q1 25 CHF 1778mn, Columvi 60m, Lunsumio 21m ( via (link) )
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24/4 08:22 af bibob |
:-)
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24/4 08:22 af bibob |
God morgen.
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23/4 20:06 af E L |
one more -
ASCO25 First data from phase 1b/2 EPCORE NHL-4: Epcoritamab (Epcor) in Chinese patients (Pts) with relapsed or refractory diffuse large B-cell lymphoma (R/R DLBCL).
Abstract: e19001
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23/4 17:32 af Solsen |
Thanks EL. Very interesting abstracts.
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23/4 16:21 af E L |
ASCO25 Novel analysis of 3-y results from the pivotal EPCORE NHL-1 study: Outcomes in patients (pts) with relapsed/refractory large B-cell lymphoma (R/R LBCL) and complete response (CR) at 2 y with epcoritamab (epcor) monotherapy.
Abstract: 7043
| Poster Bd #: 226
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23/4 16:20 af E L |
ASCO25 New Drugs in Oncology: Incorporation Into Practice - Presentation 2 -
Epcoritamab for Relapsed or Refractory Follicular Lymphoma
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23/4 16:18 af E L |
ASCO25 A phase 3, open-label, randomized study of rinatabart sesutecan (Rina-S) vs investigator’s choice (IC) of chemotherapy in patients with platinum-resistant ovarian cancer (PROC).
Abstract: TPS5627
| Poster Bd #: 520b
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23/4 16:17 af E L |
ASCO25 Rinatabart sesutecan (Rina-S) for patients with advanced endometrial cancer: First disclosure from dose expansion cohort B2 of the GTC1184-01 study.
Abstract: 3039
| Poster Bd #: 354
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23/4 16:16 af E L |
ASCO titles released.
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23/4 09:40 af E L |
more for the academics i guess, as it has been terminated - DuoHexaBody-CD37 induces direct cytotoxic signaling in diffuse large B-cell lymphoma (link)
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22/4 15:17 af E L |
(link) Teprotumumab
on EMA CHMP agenda
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22/4 13:29 af ProInvestorNEWS |
Amerikansk politik presser biotekaktierne (link)
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22/4 13:28 af ProInvestorNEWS |
Transactions in Connection with Share Buy-back Program (link)
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22/4 08:46 af JKY_VH |
Fra MW "Genmab har fået løftet kursmålet for sin amerikanske notering til 29 dollar fra 27 dollar hos den amerikanske investeringsbank Leerink Partners.
Det viser data fra Bloomberg News.
Anbefalingen er stadig "outperform".
Der går ti af Genmabs ADR-aktier på én dansk. Det nye kursmål svarer således til 1877,90 kr."
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22/4 08:45 af E L |
no, not yet Anders
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21/4 22:10 af Anders_ |
E L 15:35 Do you know what date the conference is?
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21/4 15:35 af E L |
as a reminder, we will get data on endometrial cancer in the first half of this year at a major cancer conference
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21/4 15:34 af E L |
the Rinatabart Sesutecan Ph1/2 adds an endometrial cancer cohort, 100+ extra patients (link)
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19/4 15:11 af bibob |
Er der nogen der har adgang til ØUs artikel fra 18/4. (link)
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19/4 13:31 af lahn1 |
I forbindelsemed Abbvie's sag mod Genmab / Profound Bio, vil jeg høre om der er interesse for at indsamle ca. 305 USD til Proinvester så Helge og medarbed kan downloade Abbvie's indsendte beviser De ligger uploaded på PACER og kan downloades mod betaling af 0,10 USD or side. Beviserne dækker 3003 sider.
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18/4 11:19 af lahn1 |
Thx EL I can only read that as very bullish.
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18/4 09:13 af E L |
EPCORE™ CLL-1 adds 120 patients , for Treatment-naïve (TN) and high risk (HR) CLL (link)
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18/4 09:07 af E L |
central nervous system (CNS)
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18/4 09:06 af E L |
small new trial by The Lymphoma Academic Research Organisation - Study of Epcoritamab in Relapsed and Refractory Primary Diffuse Large B-cell Lymphoma of the CNS Treated With Lenalidomide and Rituximab (E-REVRI) (link)
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18/4 08:26 af Stroka |
God morgen :-)
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18/4 07:52 af Helge Larsen/PI-redaktør |
Godmorgen :-)
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17/4 09:47 af E L |
A case report of a heavily pretreated pt with DLBC post CART failure who was successfully treated with epcoritamab in community practice. (link)
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17/4 09:41 af E L |
(link) DNB Markets - GENMAB
Looking beyond HexaBody-CD38
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17/4 08:12 af Stroka |
God morgen :-)
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17/4 06:58 af transalp |
Go morgen.. :)
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17/4 06:41 af Helge Larsen/PI-redaktør |
Godmorgen :-)
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16/4 15:22 af E L |
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16/4 15:21 af E L |
I noted Traverse Biotech, is looking into "raising capital to support the clinical entrance of a novel T-cell engaging (TCE) bispecific antibody, TB-Bs1, that targets ROR2 in solid tumor cancers."
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16/4 10:33 af gentogen |
Angående Sukkeralf 19.30.JNJs succes med Duobody taget i betragtning kan det måske godt blive interessant at høre, hvordan det ser ud med det fremadrettet hos JNJ. De har i øvrigt en fantastisk evne til så godt som aldrig at nævne Duobody og de har jo heller ikke flere licenser.
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16/4 08:13 af E L |
Barclays Buy Kr.2,100.00 Maintained 15-4-25
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15/4 19:30 af Sukkeralf |